Some inflammatory eye diseases become severe enough that standard treatments like eye drops or oral medications are no longer effective. In these situations, ophthalmologists may recommend intravenous (IV) infusion therapy to help protect vision and control inflammation.
What Eye Conditions Require IV Infusion Therapy?

IV infusion therapy is most commonly used for severe autoimmune and inflammatory eye diseases that threaten long-term vision.
Conditions frequently treated with infusion therapy include:
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- Uveitis
- Scleritis
- Ocular cicatricial pemphigoid
These conditions often require aggressive systemic treatment when inflammation becomes difficult to control.
Why Are These Conditions So Serious?

Inflammation inside or around the eye can damage delicate ocular structures if left untreated.
Without proper management, severe ocular inflammation may lead to:
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- Permanent vision loss
- Retinal damage
- Scarring
- Increased eye pressure
- Chronic pain
Early specialist evaluation is essential for protecting vision.
Why Might Standard Treatments Not Work?
Many patients initially receive treatment with:
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- Steroid eye drops
- Oral steroids
- Oral immunosuppressive medications
However, some patients either fail to respond adequately or develop side effects that limit long-term use.
IV infusion therapy allows physicians to deliver highly targeted immunomodulatory medications capable of controlling severe inflammation more effectively.
What Medications Are Used?
Treatment plans vary depending on the patient’s diagnosis and disease severity.
Common infusion medications may include:
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- Infliximab
- Rituximab
- Tocilizumab
- Solu-Medrol
- Teprotumumab
Patients are monitored closely throughout treatment by ophthalmologists and infusion specialists.
Advanced Treatment Options for Complex Inflammatory Eye Disease
MERSI provides specialized ophthalmic infusion therapy for patients throughout the Greater Boston area. Our integrated infusion suite allows patients to receive laboratory testing, physician oversight, and IV treatment within one coordinated ophthalmology practice.
FAQs
What eye diseases may require IV treatment?
Severe inflammatory conditions such as uveitis, scleritis, and ocular cicatricial pemphigoid may require infusion therapy.
Why would eye drops not be enough?
Some inflammatory diseases become too severe to control with topical medications alone.
Is infusion therapy common in ophthalmology?
No. Dedicated ophthalmic infusion suites are relatively rare.